• Trusted worldwide

    A legacy built on trust and expertise.

  • Rooted in science

    Guided by probiotic research.

  • Commitment to quality

    Ensuring potency and reliability.

  • Designed for diverse needs

    Supporting gut and women's health.

    VSL#3Benefits:

    A Clinically Studied Medical Food
    VSL#3 is a medical-grade formulation supported by clinical research.

    Ultra-High Potency, Guaranteed

    Contains 112.5 billion live bacteria (CFU) per capsule — an ultra-high-potency formula designed to keep its labeled potency through expiration when stored under recommended conditions.

    Multi-Strain

    8 complementary strains from 3 different genera.

    Science Over Hype. Purpose Over Promises.

    Built on the legacy of VSL#3 — a probiotic trusted by healthcare professionals and recognized for its scientific rigor — VSL Probiotics continues to advance microbiome science through targeted, high-quality formulations that support both clinical dietary management and everyday wellness.

     

    Committed to Potency

    Potent probiotic formulations guaranteed to maintainlabeled CFU counts through expiration.

    For us, potency isn't a number—it's a principle. Every VSL Probiotics formulation is developed with meaningful levels of live bacteria, manufactured under controlled conditions, and verified to maintain the labeled CFU count through expiration when stored as recommended.
    Potency matters because probiotic function depends on both the quantity and vitality of live organisms that reach the gut. Even modest loss over time can affect performance, which is why every VSL Probiotics product is designed and tested to deliver consistent strength from first dose to last.

    Designed for Viability

    Carefully designed formulations that help safeguard live bacteria from production to delivery.

    For probiotics to work, live microorganisms must survive both storage and digestion to reach the gut intact. Every VSL Probiotics formulation is developed with this in mind —combining carefully selected strains, stability-enhancing formulation design, and packaging to maintain viability from manufacturing through expiration.
    VSL#3 is maintained under strict cold-chain conditions — refrigerated throughout production, storage, and shipping — to help preserve live strains at their intended strength.

    Science-Led Strain Selection

    Thoughtfully formulated with complementary probiotic strains chosen for function and purpose.

    Our formulations are grounded in science. Each strain is selected for its documented characteristics and ability to contribute meaningfully to a balanced microbiome. This approach draws on years of probiotic research — building on well-studied formulations and evidence-backed strains to create products designed for specific microbiome needs. Across the VSLR Probiotics family, every formulation follows the same principle: science guides each step, from strain selection to finished product. This consistent, evidence-based process ensures reliability and quality across the brand's entire portfolio.

    A Legacy of Expertise

    A probiotic heritage recognized for its consistency, credibility, and professional trust.

    VSL Probiotics builds on the legacy of VSL#3 — a formulation long trusted by healthcare professionals for its quality and reliability.
    Our focus is clear: to create formulations grounded in evidence, crafted with precision, and respected for their consistency — not driven by trends, but by trust earned through experience.

    • Dairy-Free

    • Gluten-Free

    • Soy-Free

    • Nut-Free

    • Vegan

    • No GMOs

      Clean Ingredients. Trusted Standards.

      Dairy-Free

      Gluten-Free

      Soy-Free

      Nut-Free

      No GMOs

      Vegan

      The VSL Probiotics Difference

      Medical Foods & Supplements

      From medical foods formulated for the dietary management of Gl conditions to supplements for daily wellness, VSL Probiotics is made to the highest standards of quality and consistency.

      Proven Potency

      Up to 900 billion live bacteria per serving — verified to maintain labeled CFU counts through expiration when stored as recommended.

      Evidence-Based Formulations

      Formulated with probiotic strains and combinations supported by published research and guided by microbiome science.

      Trusted by Professionals

      Rooted in the heritage of VSL#3—a probiotic trusted by healthcare professionals—VSL Probiotics carries that same dedication to quality and research into every new formulation.

      VSL#3 Capsules are an ultra-high-potency probiotic medical food formulated to support the dietary management of IBS and ulcerative colitis. Each capsules provides 112.5 billion live bacteria from 8 clinically studied probiotic strains working together.

      FAQS

      VSL#3R is an ultra-high-potency probiotic medical food intended for the dietary management of irritable bowel syndrome (IBS), ulcerative colitis (UC), and an ileal pouch (pouchitis).

      VSL#3 should be stored under refrigeration at 36-46°F (2-8°C) to preserve potency. It can remain at room temperature for up to 2 weeks without reducing effectiveness.

      Medical foods are formulated for the dietary management of diseases or conditions with distinctive nutritional needs that cannot be met by diet alone. Unlike dietary supplements, medical foods are intended for use under a healthcare provider's supervision.

      In a 2021 clinical study, VSL#3 demonstrated dietary management outcomes in people with IBS comparable to those achieved with a low FODMAP diet1 — a commonly recommended but restrictive approach. Because VSL#3 is certified FODMAP Friendly, it can also be used alongside a low FODMAP diet for flexible dietary management.

      1Ankerson L, et al. J Med Internet Res. 2021; 23(12): e30291.